THEME
A Discovery of Witchesby Deborah Harkness

Magic vs. Science and Reason

Magic vs. Science and Reason

What This Theme Explores

A Discovery of Witches treats Magic vs. Science and Reason not as enemies, but as entwined methods of knowing. The novel asks whether empirical rigor and intuitive wonder can co-exist, and what is lost when one is exalted at the expense of the other. Through Diana Bishop, a scholar who suppresses her witchcraft, and Matthew Clairmont, a vampire-geneticist who unites data with mystery, the story probes how identity, history, and knowledge are shaped by this tension. Ultimately, it suggests that understanding deepens when reason and enchantment collaborate rather than compete.


How It Develops

At the outset, Diana polices a strict border between her academic life and her magical heritage. Her research on the historical triumph of science over magic mirrors her personal refusal to use spells, and the Bodleian Library seems to promise a sanctuary of secular reason—until the bewitched manuscript, Ashmole 782, surfaces there. That encounter punctures her illusion that scholarship exists apart from the uncanny.

The middle of the novel reframes the conflict as a false dichotomy. Matthew models synthesis: his lab deploys genetics and neuroscience to study creatures, yet he never treats magic as superstition to be debunked. Their joint pursuit of Ashmole 782 demands both methodological precision and witch-born intuition, pushing Diana to see alchemy not just as a precursor to chemistry but as a holistic practice that once wove the material and the mystical together.

By the end, Diana accepts that her intellect and magic are interdependent. The crisis of creature decline is posed as an evolutionary and genetic problem solvable only through a magical artifact—science needs enchantment’s key, and enchantment needs science’s questions. When Diana and Matthew choose to timewalk to secure training, the decision is both strategically rational and unabashedly magical, crystallizing the theme’s movement from opposition to integration.


Key Examples

  • Diana’s first encounter with Ashmole 782 exposes her self-imposed divide: she wants a life ruled by footnotes, not spells, yet a bewitched text calls her intellect and lineage into dialogue. The moment reveals how denial of magic is also a denial of self, and how scholarship can be a conduit, not a shield, for the uncanny.

    Here, with my hard-earned doctorate, tenure, and promotions in hand and my career beginning to blossom, I’d renounced my family’s heritage and created a life that depended on reason and scholarly abilities, not inexplicable hunches and spells. — Chapter 1-5 Summary

  • Alchemy becomes the battleground for definitions of knowledge when Diana clashes with her aunt, Sarah Bishop. Their debate shows how labels—“science” versus “magic”—often mask a shared pursuit of transformation and understanding, and how Diana’s interpretive frame must widen to accommodate both.

  • Matthew’s research program embodies synthesis: as a vampire and leading scientist, he refuses to treat magic as irrational. His hypothesis about creature decline is argued with data, not dogma, demonstrating that the supernatural can be approached with scientific rigor without evacuating its awe.

    Matthew was convinced that creatures were slowly becoming extinct. Hamish had dismissed his friend’s hypotheses at first, but he was beginning to think Matthew might be right. — Chapter 6-10 Summary

  • In the lab, the genome itself becomes a bridge between worlds: chromosomal differences render magic legible to science. By reframing powers as inheritable biology, the novel shows that explaining the wondrous need not diminish it; explanation can dignify the mysterious by making it part of nature’s order.

    “Humans have twenty-three chromosomal pairs in every cell nucleus, each arranged in long code sequences. Vampires and witches have twenty-four chromosome pairs.” — Chapter 31-35 Summary


Character Connections

Diana’s arc is the theme’s backbone. As a historian trained to prize sources and skepticism, she worries that embracing magic will discredit her scholarship. Yet her growth reveals that rigorous inquiry and intuitive practice can reinforce each other: her research habits sharpen her spellwork, and her burgeoning powers open questions her scholarship alone could not ask.

Matthew enacts the reconciliation Diana is learning to accept. Having witnessed the scientific revolution and now advancing contemporary genetics, he refuses to collapse his identity into “rationalist” or “creature.” His example challenges binaries: he uses reason to investigate magic, not to exile it, positioning science as a language for wonder rather than its censor.

Stephen Proctor, Diana’s father, provides an ancestral template for balance. As an anthropologist and a wizard, he practiced dual fidelity: empirical study of cultures alongside lived magic. His legacy hints that the integration Diana struggles to achieve is not unprecedented but recoverable, a tradition eclipsed by modern compartmentalization.


Symbolic Elements

  • Ashmole 782: A bewitched alchemical manuscript that predates the split between magic and science, it literalizes the theme’s synthesis. It is both an enchanted object and a repository of biological truth, and unlocking it requires scholarly diligence and witchcraft in tandem.

  • Alchemy: More than a historical curiosity, alchemy symbolizes a worldview that refused to separate matter from spirit. Diana’s initial effort to sanitize it as “proto-chemistry” is challenged by others who see its magic, urging a return to holistic knowledge.

  • Matthew’s Laboratory: A cathedral of centrifuges and sequencers devoted to studying vampires, witches, and daemons, it collapses the supposed distance between the rational and the supernatural. Here, fluorescent gels and ancient lineages share the same inquiry.


Contemporary Relevance

In an era that often pits data against intuition and “hard science” against lived experience, the novel argues for epistemic humility and breadth. It invites a public conversation in which explanation does not automatically disenchant, and mystery does not automatically reject evidence. Against polarized debates over what counts as “real,” A Discovery of Witches models a curiosity that asks better questions by letting multiple ways of knowing speak to one another.


Essential Quote

“Humans have twenty-three chromosomal pairs in every cell nucleus, each arranged in long code sequences. Vampires and witches have twenty-four chromosome pairs.”

This line distills the novel’s ethic: magic is not the enemy of reason but a phenomenon that can be described, tested, and still revered. By placing the supernatural within a biological framework, the book suggests that comprehension deepens wonder rather than erasing it—science becomes a means of seeing magic more clearly, not denying it.